Foundation grantees answer some complex questions of pregnancy in lupus

Lupus Foundation of America

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Hydroxychloroquine may be able to prevent congenital heart block, an irreversible and life-threatening condition, in unborn children of pregnant women with lupus, according to preliminary results of a study funded by the Lupus Foundation of America.  One of the Foundation’s 2014 LIFELINE Grant ProgramTM recipients, Jill Buyon, MD, New York University (NYU) Langone School of Medicine, recently presented these preliminary results at the 2015 NYU Seminar in Advanced Rheumatology. Her study is known as the Preventive Approach to Congenital Heart Block with Hydroxychloroquine (PATCH) study. Last year, the Foundation introduced the LIFELINE Grant Program as part of its National Research Program to fill gaps in funding due to decreased federal research grants.  LIFELINE has allowed Dr. Buyon to continue this very important work in lupus research.

Also presented at the NYU Seminar was the Predictors of PRegnancy Outcome: BioMarkers In Antiphospholipid Syndrome and Systemic Lupus Erythematosus (PROMISSE) study. The 10-year study was created and led by the 2014 co-recipient of the Foundation’s Evelyn V. Hess Award, Jane Salmon, MD, Hospital for Special Surgery in New York. The results of Dr. Salmon’s study have helped identify risk factors and predictors of adverse pregnancy outcomes in women with lupus. This information will be used in clinical practice to better guide the management of lupus and pregnancy.

The Evelyn V. Hess Award, established in 2005, is presented each year to an investigator whose work has significantly advanced understanding of the causes and management of lupus.  Dr. Hess is an internationally known expert in lupus, with a special interest in environmental aspects of the disease. She is a master of both the American College of Rheumatology and the American College of Physicians and a fellow of the American Association for the Advancement of Science, the American Academy of Allergy and Immunology and the Royal Society of Medicine. 

Learn more about the latest findings in lupus pregnancy that were presented at the 2015 NYU Seminar.