Avise® SLE test can confirm a lupus diagnosis while ruling out similar diseases and conditions

Lupus Foundation of America

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What is the purpose of the Avise SLE Test?

There is no single laboratory test to determine whether a person has lupus. Many different factors, including laboratory tests, are taken into consideration to make a diagnosis. 

In any medical situation, knowing the correct diagnosis and learning it quickly are crucial factors in enabling physicians to select the most appropriate treatment in a timely manner. But this is especially important for people with lupus because every day without treatment can mean dangerous and possibly permanent damage to the heart, lungs, kidneys, skin, and other organs. During the process, The Avise® Lupus test, can help rule in lupus, while ruling out other potential diseases, making the diagnosis process quicker and more accurate. 

How was this test started?

In 2008, the Lupus Foundation of America funded research  that supported the hypothesis that measuring a specific complement protein, named C4d, might be a more useful tool than many of the other tests currently used to diagnose and monitor lupus. After years of additional research, including a large study to validate the new test, the Avise® SLE test was made publically available. The Avise® SLE test, combines different biomarkers and improves the accuracy of diagnosing lupus. 

Are these tests right for me?

There are many situations in which a health care provider could use the Avise® Lupus test: for example, it may be used to confirm a lupus diagnosis in a person who is ANA-positive and has been referred by a primary care provider; to differentiate a lupus diagnosis from a diagnosis of any other connective tissue disease; to confirm the lupus diagnosis prior to recommending therapy; or to retest a person whose past connective tissue disease test results were inconclusive. 

Speak with your health care provider about what's right for you.